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We hypothesized that increased oxidative stress and reactive oxygen species (ROS) levels, similar to Gb3 accumulation, are involved in renal remodeling in Fabry disease 22,23,24,25,26,27,28
Neisseria meningitidis serogroup B
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The mechanisms of action involve modulation of sleep-regulating neurotransmitters and neuroendocrine systems including enhancement of delta wave activity during deep sleep stages, regulation of cortisol and stress hormone rhythms that impact sleep quality, optimization of circadian rhythm signaling for proper sleep-wake cycles, support for melatonin and sleep-promoting pathways, and modulation of pain perception which can interfere with sleep quality