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Moreover, allicin also regulates the metabolites of gut microbiota, such as upregulating SCFA, while downregulating secondary BAs, TMAO, and indoles, stimulating brown adipose tissue activation, browning in white adipose tissues (Zhang et al., 2020), decline in lipid accumulation in the liver, and weight loss in obese mice (Shi et al., 2019)

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159 In a nonalcoholic fatty liver mouse model, the β-diversity of cecal microbiota changes significantly, where Blautia , Unidentified-Lachnospiraceae , Romboutsia , Faecalibaculum , and Ileibacterium abundance increase significantly, while Allobaculum and Enterorhabdus decrease significantly