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Maui natives Kumu Hula Kawaiola Noelani Deguilmo and Po'o Pua'a Kapeka Vares pose in front of desert landscape in their new home of Reno, Nevada. | Smithsonian Photo Contest | Smithsonian Magazine
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However, nicotine also acts as an agonist on nicotinic acetylcholine receptors (nAChRs), which play a key role in regulating neurotransmitter release, neuronal excitability, and cognition ( Nicotine has neuroprotective capabilities largely attributed to its ability to initiate protective signaling transduction that enhances dopamine release and reduces neurotoxicity
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