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Published in-vitro and preclinical work has examined GHK-Cu as a bound-copper carrier in copper-dependent signalling and extracellular-matrix models, KPV as a C-terminal α-MSH fragment in melanocortin-linked and NF-κB-related signalling assays, BPC-157 as a probe for peptide-mediated signalling in cellular models, and TB-500 in actin-binding and cell-migration work