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Recently a conserved stem-loop structure within the NS5B coding region, 5BSL3.2, was found to be required for RNA replication 78

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While heterologous desensitization of the β 2 AR was mediated primarily by PKA, a novel catecholamine-activated cAMP-independent kinase, termed βAR kinase (βARK, later named GRK2), was responsible for the process of homologous desensitization [11, 12]