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CISD1 and CISD2 were discovered as unexpected targets for the peroxisome proliferator activated receptor gamma (PPARG) agonist pioglitazone ( As expected, increased CISD1 expression suppresses erastin-induced ferroptosis in human hepatocellular carcinoma cells by limiting mitochondrial iron uptake (Yuan et al., 2016a)
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Nouri, K., Feng, Y
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