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Abbreviations ASK1: apoptosis signal-regulating kinase 1 BDNF: brain-derived neurotrophic factor CNPase: 2′,3′-cyclic nucleotide 3′-phosphodiesterase CNS: central nervous system Dock3: dedicator of cytokinesis 3 EAE: experimental autoimmune encephalomyelitis GEF: guanine nucleotide exchange factor MAPK: mitogen-activated protein kinase MBP: myelin basic protein mfERG: multifocal electroretinogram MS: multiple sclerosis NMDA: N-methyl-D-aspartate RGC: retinal ganglion cell RRMS: relapsing-remitting multiple sclerosis References Namekata K, Kimura A, Kawamura K, Harada C, Harada T
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According to these assumptions, arginine metabolism appears to act as a compensatory mechanism for reduced glutathione levels
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