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Dixon first discovered and named ferroptosis, the critical role of GPX4 in the inhibition of ferroptosis in his study has received widespread attention, mainly in the antioxidant axis system x c - -GSH-GPX4 ( c - is inhibited, obstruction of the cystine transport pathway can decrease GSH and GPX4, which can lead to cell death due to ongoing oxidative stress ( Figure 1A )

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These anti-EMT effects were facilitated by inhibition of the Akt/ERK signaling pathway, displaying the potential of isorhamnetin as a therapeutic compound to treat or restrict NSCLC progression and metastasis [96]

and Glycine