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Because NNMT consumes nicotinamide, blocking the enzyme preserves more nicotinamide for the NAD+ salvage pathway, increasing intracellular NAD+ concentration in treated cell models
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— 5-Amino-1MQ NNMT inhibitor research (PubMed) NIH NLM — NNMT inhibition and metabolic research ClinicalTrials.gov — Search: 5-Amino-1MQ Research Research Use Only
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