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The cause of this condition seems to be disturbances in the recognition of pathogens microorganisms in the human intestine determined by alterations in the expression of pathogen recognition receptors, which include the already mentioned NOD2 (336, 340) and also TLRs and Rig-I like receptors
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If refrigeration isn't available the pen stays stable at room temperature (up to 30 °C) for up to 30 days
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