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The observed decrease in GPx4 activity after TBI, along with these findings, suggests that the System Xc−/GSH/GPX4 pathway plays an important role in the activation of ferroptosis following TBI (Figure 3D
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Leiomyoma cells are severely hypoxic and such oxygen-limited microenvironment protects leiomyoma cells against apoptosis and maintains a proliferative state [48]
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