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CD47 the surface protein CD47 is a receptor that binds to signal-regulatory protein alpha (SIRPα) or thrombospondin-1 (TSP-1) and acts as a signal to inactivate the phagocytosis in macrophages
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One reason for the contradictory results of RGD-GHK binding in vitro and in vivo could be that high-molecular-weight peptide hindered the penetration and retention of sOtx2-GHK in the skin
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