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Soon, the identification of several mechanisms on how LD was able to modulate the activity of transferred immune-effector cells was initiated, including its modulation of homeostatic cytokines such as IL-7 and IL-15 by abrogation of cellular cytokine ‘sinks’, or other immune cells that compete with transferred immune-effector cells for the consumption of stimulatory cytokines
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3,18 We also observed that BT474 persister cells allowed to regrow after washout of lapatinib retain their full sensitivity to RSL3 for at least two weeks but for less than two months (Fig
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