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Lower GSH levels can occur because LC is not available in the food consumed, or it can result from the consumption of an energy-rich diet, which increases ROS and oxidative stress
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In addition, by generating a phosphorylated chimeric protein (ClACCp) containing clathrin heavy chain (CHC) (aa1โ574) and CHC interaction domain (TACC3 CID , aa549โ570) of TACC3 (a member of the transforming acidic coiled-coil family of proteins separated by four repeats of Thr-Gly-Ser linkers (TGS4) with pSer incorporation of at TACC3 residue 558 (ClACCp) using the same SepRS/tRNA, 45 Burgess et al
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