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One report indicated that CAV-1 is homologous to the SOCS pseudosubstrate and functions as a negative regulator of STAT signaling, and that CAV-1 prevents the binding of JAKs and STAT proteins to their receptors by binding phosphotyrosine residues of cytokine receptors 22

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Some studies also recommend measuring baseline serum antioxidant levels prior to administering them as supplements to ensure that patients will benefit from these antioxidants