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The brain basis, per the late Judith Rapaport at NIH: the basal ganglia — circuits involved in generating action, with an accelerator and a brake — show enlargement of subregions in true clinical OCD
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Residues in the ATP binding pocket of St-GSS1 are highly conserved in sequence and position in the Gpa-GSS22 structure (13/15 residues, S4 Table), and similarly conserved in sequence across G
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