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However, the EAATs include EAAT1 (SLC1A3), EAAT2 (SLC1A2), EAAT3 (SLC1A1), EAAT4 (SLC1A6), and EAAT5 (SLC1A7) can use aspartate and glutamate as substrates ( - dependent, Na + -independent manner ( Figure 1C ) ( 2+ followed by a decrease in cell viability ( In non-neuronal cancer cells, in contrast, the upregulation of the expression of EAATs can promote tumor growth and invasion
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