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Pitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: An elephant in the room - ScienceDirect
In tumor-associated macrophages, which are mainly derived from circulating monocytes and are acknowledged as the most abundant leukocytes in melanoma lesions, ROS greatly enhance the secretion of tumor necrosis factor (TNF-α), thereby increasing tumor invasiveness [65]
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