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While our results are consistent with a senolytic effect of GPX4 inhibitors, the effects observed in some of the models, although significant, were modest, and we acknowledge that further investigation is needed to assess a potential translation to the clinic
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CBD reduced the cognitive deficits induced by Aβ via modulation of microglial activity, promotion of neurotrophic factor release, and regulation of inflammatory genes, such as TNF-α and monocyte chemoattractant protein-1(MCP-1) [30]
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