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Front Neurol 2024, PMID 38638315), and a Phase III successor, COURAGE-2, randomised 188 patients with acute ischaemic stroke and missed its primary endpoint: no difference in disability, daily-living scores or survival at six months (J Clin Neurosci 2026, PMID 42462342)
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The 1 μmol·L −1 SL concentration, on one hand, was specifically associated with the Turquoise module, which was enriched in “Ribosome”, “Proteasome”, “SNARE interactions in vesicular transport”, “Ribosome biogenesis in eukaryotes”, and “RNA degradation”, showing distinct positive correlations with SD, Fv / Fm , and Ci
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