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Because rigorous human clinical trials are lacking, nearly all available safety information is either anecdotal or drawn from animal studies — and neither reliably predicts what happens in humans

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HUBERMAN: And a good number of people will use it as a longevity agent based largely on animal data that it can suppress tumor growth, it can increase telomere length, and to some extent that it can recalibrate the circadian rhythm changes and the disruptions in the patterns of melatonin that occur as animals and perhaps as humans age